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Topo I Polyclonal Antibody, 50ul Filtration The 2 isoforms encoded by

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Topo I Polyclonal Antibody, 50ul Filtration The 2 isoforms encoded byTOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

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Description

The 2 isoforms encoded by these genes are not identical

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Topo I Polyclonal Antibody, 50ul Filtration The 2 isoforms encoded byTOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

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