DUSP4 Polyclonal Antibody, 20ul Cellular Function Assays regulates cell polarity and functions

regulates cell polarity and functions as a tumor suppressor

|miscellaneous:Contrarily to other members of the family that can bind several FGF receptors FGF19 is specific for FGFR4

This gene is a strong tumor suppressor for colorectal carcinoma

This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system

DUSP4 Polyclonal Antibody, 20ul Cellular Function Assays regulates cell polarity and functionsThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family