IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers a POZ/zinc finger transcription repressor

a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis

The protein encoded by TNS1 (tensin 1)localizes to focal adhesions

synaptogenesis and lymphocyte activation

which has many cysteine residues with conserved spacing

IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers a POZ/zinc finger transcription repressorThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell