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The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction

Polymorphisms in CFB are associated with a reduced risk of age-related macular degeneration

This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites

HRK Polyclonal Antibody, 100ul Recombinant Ab Production Take risks and achieve accurateThis gene encodes a member of the BCL 2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL 2 and BCL X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants.