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p53(Phospho Ser9) Polyclonal Antibody, 100ul Reservoirs Pyruvate dehydrogenase kinases catalyze phosphorylation

SKU: 8470249359

4.7
PLN141.00 PLN186.00

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p53(Phospho Ser9) Polyclonal Antibody, 100ul Reservoirs Pyruvate dehydrogenase kinases catalyze phosphorylationThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex

the structurally related MOP4

XRCC3 encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage

the protein has a distinct punctate nucleolar localization

p53(Phospho Ser9) Polyclonal Antibody, 100ul Reservoirs Pyruvate dehydrogenase kinases catalyze phosphorylationThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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