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ZnT-9 Polyclonal Antibody, 50ul[BT-AP09754] Custom RNA Oligos Two alternately spliced transcripts encoding

SKU: 84947462623

4.3
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ZnT-9 Polyclonal Antibody, 50ul[BT-AP09754] Custom RNA Oligos Two alternately spliced transcripts encodingZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent

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Description

Two alternately spliced transcripts encoding two protein isoforms have been identified

Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer

metabolic control

This protein has been shown to interact with MCM7 and DNA polymerase alpha

ZnT-9 Polyclonal Antibody, 50ul[BT-AP09754] Custom RNA Oligos Two alternately spliced transcripts encodingZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent

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