ERAP2 Polyclonal Antibody, 50ul In vitro Assessment Gene mutations that lead to

Gene mutations that lead to a loss in function are associated with increased pheomelanin production

The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation

Component of a mSin3A corepressor complex that contains SIN3A| SAP130| SUDS3/SAP45| ARID4B/SAP180| HDAC1 and HDAC2

The various isoforms have functional differences

ERAP2 Polyclonal Antibody, 50ul In vitro Assessment Gene mutations that lead toThis gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on