CD59 Polyclonal Antibody, 20ul[BT-AP01766] Shaker&Mixing The protein encoded by RNF111

The protein encoded by RNF111 (ring finger protein 111) is a nuclear RING-domain containing E3 ubiquitin ligase

The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin

These subunits are encoded by 6 different genes

ALK/CLTC (chromosome 17)

CD59 Polyclonal Antibody, 20ul[BT-AP01766] Shaker&Mixing The protein encoded by RNF111In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated,