Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation Alternate splicing results in both

Alternate splicing results in both coding and non-coding variants

In one family with congenital myasthenic syndrome affecting limb-girdle muscles| a mutation in this gene was found

The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol

Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns

Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation Alternate splicing results in bothALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes