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BLMH Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator osteogenesis imperfecta and Charcot-Marie-Tooth Disease

SKU: 86311444057

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BLMH Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator osteogenesis imperfecta and Charcot-Marie-Tooth DiseaseBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

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Description

osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3

gastrointestinal tissues and myeloid tissue

Transgenic mice overexpressing this gene exhibit defects in testis

The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1

BLMH Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator osteogenesis imperfecta and Charcot-Marie-Tooth DiseaseBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

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