Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification SUV39H1 is targeted to histone

SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes

GO annotations related to this gene include binding and RNA polymerase binding

PubMed: 18004385

The majority of autoantibodies to p70 in most sera from patients with SLE seem to be reactive with this region

Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification SUV39H1 is targeted to histoneSecreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (By similarity). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (By similarity). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (By similarity). In addition, functions as wound related growth factor that acts