RGRF1 Polyclonal Antibody, 20ul Recombinant Ab Production Sevral transcript variants encoding different

Sevral transcript variants encoding different isoforms have been found for this gene

Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body

and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions

This complex functions as an upstream activator of NF-kappaB signaling

RGRF1 Polyclonal Antibody, 20ul Recombinant Ab Production Sevral transcript variants encoding differentThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta gamma subunit. Mouse studies