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VWF Polyclonal Antibody, 100ul Cryopreservation Targeted disruption of this gene

SKU: 86927172124

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VWF Polyclonal Antibody, 100ul Cryopreservation Targeted disruption of this geneThis gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.

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Description

Targeted disruption of this gene in mice affects embryonic viability

this gene encodes a protein that is not closely related to other known growth factors

Weakly expressed in pancreas

The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells

VWF Polyclonal Antibody, 100ul Cryopreservation Targeted disruption of this geneThis gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.

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