Siah-2 Polyclonal Antibody, 100ul Yeast Expression Contains 5 WD repeats

Contains 5 WD repeats

ACVRL1 encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands

Several splice variants encoding different isoforms have been found for this gene

SFN (Stratifin) is a Protein Coding gene

Siah-2 Polyclonal Antibody, 100ul Yeast Expression Contains 5 WD repeatsSIAH2 encodes E3 ubiquitin protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.