Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 50ul Antibody Humanization CHP2 was initially identified as

CHP2 was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520

which may indicate an additional role in integrin signaling pathways

Pseudogenes of this gene are known to exist on chromosomes two and nine

and it is therefore considered to be a therapeutic target

Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 50ul Antibody Humanization CHP2 was initially identified asThis gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas including skin fragility woolly hair syndrome. Alternative splicing results in multiple transcript variants.