C1RL Polyclonal Antibody, 20ul Immunoassays Mutations in this gene or

Mutations in this gene or its regulatory region cause hypobetalipoproteinemia| normotriglyceridemic hypobetalipoproteinemia| and hypercholesterolemia due to ligand-defective apoB| diseases affecting plasma cholesterol and apoB levels

The product of this gene (solute carrier family 25 member 6) functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm

Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA

With a generous 25 cm² surface area and 50 mL capacity

C1RL Polyclonal Antibody, 20ul Immunoassays Mutations in this gene orDoes not associate with the C1 complex. According to PubMed: 15385675 doesn't cleave the proform of complement C1s.,Mediates the proteolytic cleavage of HP haptoglobin in the endoplasmic reticulum.,induction: Up regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.,Belongs to the peptidase S1 family.,Contains 1 CUB domain.,Contains 1 peptidase S1 domain.,tissue specificity: Highly expressed in placenta, liver, kidney,