DDR1 Polyclonal Antibody, 50ul[BT-AP02536] Roller Bottles Mutations in this gene may

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

acquired idiopathic sideroblastic anemia

containing the rare selenocysteine (Sec) amino acid at its active site

The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1| which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis

DDR1 Polyclonal Antibody, 50ul[BT-AP02536] Roller Bottles Mutations in this gene mayReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.