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Ku-70 (Acetyl Lys331) Polyclonal Antibody, 50ul Human Genome Knockout Libraries Some members of this protein

SKU: 87427210412

4.1
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Ku-70 (Acetyl Lys331) Polyclonal Antibody, 50ul Human Genome Knockout Libraries Some members of this proteinThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

Some members of this protein family may play a role in apoptosis

This protein may also affect cytoskeletal-membrane organization

it binds to the p53 tumor suppressor protein

PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL

Ku-70 (Acetyl Lys331) Polyclonal Antibody, 50ul Human Genome Knockout Libraries Some members of this proteinThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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