MMP-8 Polyclonal Antibody, 100ul Custom DNA Oligos Mutations in this gene cause

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins

Secretogranin-3 encoded by SCG3 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins

|PTM:Phosphorylation has no effect on Catalytic activity

MMP-8 Polyclonal Antibody, 100ul Custom DNA Oligos Mutations in this gene causeMMP8 encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N termini. This protein functions in the degradation of type I, II