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Human Transcription Factor SOX 9, SOX9 ELISA Kit, 96T Sealing Film TGF-beta-1 is released from LAP

SKU: 87579260412

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Human Transcription Factor SOX 9, SOX9 ELISA Kit, 96T Sealing Film TGF-beta-1 is released from LAP

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Description

TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1

Plays an indispensable role in the induction of IFN-gamma dependent anti-mycobacterial systemic immunity (PubMed: 26160376)

a rate-limiting step in cholesterol catabolism and bile acid biosynthesis (PubMed: 1694852

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Human Transcription Factor SOX 9, SOX9 ELISA Kit, 96T Sealing Film TGF-beta-1 is released from LAP

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