BNIP-3 Polyclonal Antibody, 50ul[BT-AP00948] Insect Expression Alternative splicing has been observed

Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats

interact with nucleic acids and have diverse functions

One isoform lacks the intermembrane region and is secreted outside the cell

this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells

BNIP-3 Polyclonal Antibody, 50ul[BT-AP00948] Insect Expression Alternative splicing has been observedBNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The encoded protein interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.