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AR Polyclonal Antibody, 100ul[BT-AP00567] Cell fragmentation and collection The encoded protein constitutes a

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AR Polyclonal Antibody, 100ul[BT-AP00567] Cell fragmentation and collection The encoded protein constitutes aThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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Description

The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved

It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain

Mice deficient for this gene have increased fat mass despite decreased food intake

GO annotations related to this gene include poly (A) RNA binding and ligase activity

AR Polyclonal Antibody, 100ul[BT-AP00567] Cell fragmentation and collection The encoded protein constitutes aThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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