PO3F2 Polyclonal Antibody, 50ul Cryopreservation Alternative splicing yields two isoforms

Alternative splicing yields two isoforms that differ in abundance and expression patterns

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs)

It is an integral membrane protein and can regulate neurotransmitter release

Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes

PO3F2 Polyclonal Antibody, 50ul Cryopreservation Alternative splicing yields two isoformsThis gene encodes a member of the POU III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.