Tuberin(Phospho Thr1462) Polyclonal Antibody, 100ul Plates & Dishes Individuals with the A

Individuals with the A

Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene

Mutations in NR3C are associated with generalized glucocorticoid resistance

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Tuberin(Phospho Thr1462) Polyclonal Antibody, 100ul Plates & Dishes Individuals with the AMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.