MARCKS Polyclonal Antibody, 50ul[BT-AP05219] Modification Enzymes The encoded protein is widely

The encoded protein is widely used as a marker for hematopoietic stem cells

This gene localizes within the class III region of the MHC on the short arm of chromosome 6

The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity

The loss of this protein correlates with uncontrolled cell growth and tumor formation

MARCKS Polyclonal Antibody, 50ul[BT-AP05219] Modification Enzymes The encoded protein is widelyMyristoylated alanine rich C kinase substrate encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking