YAP(Phospho-Ser109) Rabbit Polyclonal Antibody, 100ul Immuno Plates Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for GRM8

Several alternatively spliced transcript variants of this gene have been described

CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

and cyclin C

YAP(Phospho-Ser109) Rabbit Polyclonal Antibody, 100ul Immuno Plates Alternatively spliced transcript variants encodingThis gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development growth repair and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.