APC5 Polyclonal Antibody, 100ul Cell Dissociation and its SH2 domain binds

and its SH2 domain binds tyrosine phosphorylated sequences

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and a tyrosine kinase (TK) domain within the cytoplasmic domain

These proteins share considerable sequence similarity over the N-terminal portion of the molecule

APC5 Polyclonal Antibody, 100ul Cell Dissociation and its SH2 domain bindsANAPC5 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex cyclosome (APC C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B type cyclins for 26S proteasome mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC C and for the