Raf-1 Polyclonal Antibody, 100ul[BT-AP07628] Plasmid Preparation Two similar genes are located

Two similar genes are located nearby on chromosome 7q22 and a pseudogene is found on chromosome 7p13

is involved in cell cycle progression

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GAB2 (GRB2 associated binding protein 2) is a member of the GRB2-associated binding protein (GAB) gene family

Raf-1 Polyclonal Antibody, 100ul[BT-AP07628] Plasmid Preparation Two similar genes are locatedRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine