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IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts and contains two phopshotyrosine-binding domains

SKU: 8961703950

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IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts and contains two phopshotyrosine-binding domainsThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

and contains two phopshotyrosine-binding domains (PTB1 and PTB2)

a two-carbon substrate

This gene is expressed in the inner ear and bladder epithelium

Mixed lineage kinase domain-like protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis

IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts and contains two phopshotyrosine-binding domainsThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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