HABP2 Rabbit Polyclonal Antibody, 100ul Funnels and hereditary hemorrhagic telangiectasia syndrome

and hereditary hemorrhagic telangiectasia syndrome

The encoded protein plays a role in DNA repair and homologous recombination

MIM 300161)

A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters

HABP2 Rabbit Polyclonal Antibody, 100ul Funnels and hereditary hemorrhagic telangiectasia syndromeThis gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with