MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter The encoded protein has been

The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

This protein tethers E3 dimers to the E2 core of the PDH complex

A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17

MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter The encoded protein has beenThe protein encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.