NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in a

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

It is present with an interindividual variation in copy number and between 20 to 103 copies can be found both on chromosome 4 and chromosome 8

are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin

The exact function of the encoded protein is not known

NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in aThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.