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RHG06 Polyclonal Antibody, 100ul Endonucleases & Exonucleases These family members contain multiple

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RHG06 Polyclonal Antibody, 100ul Endonucleases & Exonucleases These family members contain multipleThis gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have

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Description

These family members contain multiple N-terminal leucine-rich repeats| in addition to a C-terminal calponin homology domain| a type of domain that mediates interactions with actin filaments

and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains

Histone deacetylation modulates chromatin structure

Neuromodulin encoded by GAP43 has been termed a ‘growth' or ‘plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration

RHG06 Polyclonal Antibody, 100ul Endonucleases & Exonucleases These family members contain multipleThis gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have

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