Srb7 Polyclonal Antibody, 50ul Variant Libraries The PWWP2B protein is phosphorylated

The PWWP2B protein is phosphorylated upon DNA damage

Alterations in this region have been associated with the Beckwith-Wiedemann syndrome

Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes

|Belongs to the histone deacetylase family

Srb7 Polyclonal Antibody, 50ul Variant Libraries The PWWP2B protein is phosphorylatedMED21 (mediator complex subunit 21) encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of MED21 is located on chromosome 8. Alternative splicing results in multiple transcript variants.