AP2M1 Polyclonal Antibody, 50ul Custom RNA Oligos Two molecules of each of

Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes

each domain consists of 6 transmembrane segments and intra- and extracellular linkers

Mutations in CYP27A1 cause cerebrotendinous xanthomatosis

This gene may play a role in the progression of several malignancies including melanoma

AP2M1 Polyclonal Antibody, 50ul Custom RNA Oligos Two molecules of each ofThis gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA 4 protein.