ZPI Polyclonal Antibody, 100ul Erlenmeyer Flasks Both XRCC4 and DNA-PK are

Both XRCC4 and DNA-PK are known to be required for NHEJ

Isoform 1 has lower affinity for DNA

Two messages have been detected on northern blots but the larger message has not been characterized

This PDE has dual-specificity for the second messengers

ZPI Polyclonal Antibody, 100ul Erlenmeyer Flasks Both XRCC4 and DNA-PK areThe protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.