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Crk-L(Phospho Tyr207) Polyclonal Antibody, 20ul Micro Centrifuge Tubes This gene has been identified

SKU: 91116203396

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Crk-L(Phospho Tyr207) Polyclonal Antibody, 20ul Micro Centrifuge Tubes This gene has been identifiedThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.

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Description

This gene has been identified as a tumor suppressor gene in several types of cancer

In response to DNA damage and replication blocks

RPS6KL1 contains one MIT domain and a protein kinase domain

thyroid follicular carcinomas and atypical follicular thyroid adenomas

Crk-L(Phospho Tyr207) Polyclonal Antibody, 20ul Micro Centrifuge Tubes This gene has been identifiedThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.

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