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JAK2 Polyclonal Antibody, 50ul[BT-AP04689] Diagnostic Probes & Oligos Mutations in this gene have

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JAK2 Polyclonal Antibody, 50ul[BT-AP04689] Diagnostic Probes & Oligos Mutations in this gene haveTyrosine protein kinase JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

Mutations in this gene have been associated with asthma

May also be activated by intracellular calcium store depletion

|Transcriptional repressor which is required for germinal center formation and antibody affinity maturation

Involved in LPIN1 dephosphorylation

JAK2 Polyclonal Antibody, 50ul[BT-AP04689] Diagnostic Probes & Oligos Mutations in this gene haveTyrosine protein kinase JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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