Vav3 Polyclonal Antibody, 50ul Cell Screening and Imaging The function of the fiber

The function of the fiber cell membrane protein encoded by this gene is undetermined

The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3

A pseudogene is located on chromosome 11

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Vav3 Polyclonal Antibody, 50ul Cell Screening and Imaging The function of the fiberVAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding