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TM4SF1 Polyclonal Antibody, 100ul Roller Bottles Mutations in this gene cause

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TM4SF1 Polyclonal Antibody, 100ul Roller Bottles Mutations in this gene causeThe protein encoded by TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different

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Description

Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor

This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes| thymus| spleen| and bone marrow

is found in azurophil granules of neutrophilic polymorphonuclear leukocytes

The arachidonate 5-lipoxygenasen

TM4SF1 Polyclonal Antibody, 100ul Roller Bottles Mutations in this gene causeThe protein encoded by TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different

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