MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody, 20ul Bottles A mutation in the mouse

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

The coiled-coil motif is involved in homodimerization| the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity| and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes

myoclonic epilepsy

with monocyte chemotactic and antimicrobial activity

MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody, 20ul Bottles A mutation in the mouseThe protein encoded by this gene is one of the highly conserved mini chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4 6