ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges Although three transcripts are detected

Although three transcripts are detected in northern blots

miscellaneous:Knockdown significantly reduces the adhesion of cancer cells to lung microvascular endothelial cells and the reciprocal effect is observed following overexpression

Mutations in this gene have been associated with chronic granulomatous disease

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ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges Although three transcripts are detectedThis gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain proline rich region and Src homology 3 (SH3) domain and are components of the Abi WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21 activated kinase. Alternative splicing