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Phospho-ATF-2 (T69) Polyclonal Antibody, 50ul Cell Senescence Receptor tyrosine-protein kinase erbB-2 has

SKU: 92757864775

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Phospho-ATF-2 (T69) Polyclonal Antibody, 50ul Cell Senescence Receptor tyrosine-protein kinase erbB-2 hasATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This protein is also a

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Description

Receptor tyrosine-protein kinase erbB-2 has no ligand binding domain of its own and therefore cannot bind growth factors

Loss of function or expression of this gene has been detected in multiple tumors

It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription

Troponin I (TnI)| along with troponin T (TnT) and troponin C (TnC)| is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle

Phospho-ATF-2 (T69) Polyclonal Antibody, 50ul Cell Senescence Receptor tyrosine-protein kinase erbB-2 hasATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This protein is also a

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