PLUNC Polyclonal Antibody, 50ul Enzymes & Activity Assays a GTPase-activating protein (GAP) domain

a GTPase-activating protein (GAP) domain

TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22

and E exhibiting the highest degree of conservation

GO annotations related to this gene include RNA binding and RNA-3-phosphate cyclase activity

PLUNC Polyclonal Antibody, 50ul Enzymes & Activity Assays a GTPase-activating protein (GAP) domainBPIFA1 (BPI fold containing family A member 1) is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis