Raf-1 Polyclonal Antibody, 100ul[BT-AP13536] Nucleic Acid Extraction Mutations in this gene are

Mutations in this gene are associated with autosomal recessive retinitis pigmentosa

Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation

They are very similar and it is therefore difficult to provide a clear and unambiguous protein sequence

This gene encodes a member of the NF-kappa-B inhibitor family| which contain multiple ankrin repeat domains

Raf-1 Polyclonal Antibody, 100ul[BT-AP13536] Nucleic Acid Extraction Mutations in this gene areThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.