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Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction it is required for maximal

SKU: 93238992786

4.2
PLN123.75 PLN170.75

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Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction it is required for maximalThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

it is required for maximal ATPase activity of BRG1

or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL

The membrane-bound form has both membrane-binding and catalytic domains

and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences

Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction it is required for maximalThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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