ZIM2 Rabbit Polyclonal Antibody, 20ul Sampling Tubes Humans have six elastase genes

Humans have six elastase genes which encode the structurally similar proteins elastase 1

The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division

Related pseudogenes have been identified on chromosome 15

ZIM2 Rabbit Polyclonal Antibody, 20ul Sampling Tubes Humans have six elastase genesIn human ZIM2 and PEG3 (GeneID: 5178) are two distinct genes that share a set of 5' exons and have a common promoter and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2 or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow where ZIM2 and PEG3 genes do not share exons in common and the imprinting status of ZIM2 is also not conserved