Ob-R Polyclonal Antibody, 20ul[BT-AP06324] Cryopreservation CBL has been found to

CBL has been found to be mutated or translocated in many cancers including acute myeloid leukaemia

Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis

a type I TARP and a calcium channel gamma subunit

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Ob-R Polyclonal Antibody, 20ul[BT-AP06324] Cryopreservation CBL has been found toThe protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with