BID (p11| Cleaved-Ser100) Rabbit Polyclonal Antibody, 50ul Plasmid Preparation qPCR probes
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BID (p11| Cleaved-Ser100) Rabbit Polyclonal Antibody, 50ul Plasmid Preparation qPCR probesIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by
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