Rat Interferon Gamma, IFN-G ELISA Kit, 96T Enzymes & Activity Assays It is also cleaved by

It is also cleaved by caspase-3 in vitro

Also acts as a serine protease inhibitor: negatively regulates Matrix Metalloproteinase-9 (MMP9) by suppressing MMP9 secretion and by direct inhibition of its enzymatic activity (PubMed: 9789069

and is known to be an important tumor suppressor gene

Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (PubMed: 20364084

Rat Interferon Gamma, IFN-G ELISA Kit, 96T Enzymes & Activity Assays It is also cleaved byProduced by lymphocytes activated by specific antigens or mitogens. IFN gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.